Pharmaceutical, OSD Manufacturing

Pharmaceutical, OSD Manufacturing

Comply with the stringent health and safety requirements in pharmaceutical production while meeting mandatory quality requirements.

More and more, pharma manufacturers are looking for ways to reduce the costs associated with product manufacture yet increase safety and quality. Cleanroom air filtration and process dust collection solutions play a key role in ensuring the manufacture of high-quality pharmaceutical products while helping you increase your throughput.

 

Oral solid dosage (OSD) processes face two main challenges. For one, the generic drug market is putting pressure on manufacturing operations to become more agile and efficient. Filtration systems at these facilities have the potential to help lower operating costs by cutting energy consumption and equipment downtime and by providing filters with an extended lifetime.

 

Secondly, drugs containing high-potency compounds and active pharmaceutical ingredients (HPAPIs), like in oncology treatments, are on the rise. Their production demands enhanced operational quality and occupational safety to eliminate cross-contamination risks and to protect people and the environment. Operational flexibility also presents a challenge, requiring high quality while allowing for rapid production changeovers.

 

Different facility areas have different cleanliness requirements

Camfil provides state-of-the-art HEPA filters and specialised dust collectors for OSD processes and facilities. OSD facilities consist of different areas that each require their own air filter or dust collector to meet various needs:

 

Area

Solution

MAU and AHU

High-end pre-filtration for minimising total cost of ownership and protecting critical areas

Milling, grinding, blending, formulating

Compression suites

Coating areas

Efficient HEPA filter systems for smooth cleanroom operations – Camfil CleanSeal™ and Megalam™

Compact dust collectors – Camfil Quad Pulse Packages 1 and 2

Isolator areas

Downflow booths

Megalam and push-push filters for work environment protection

Conveying and loading areas

CamCleaner™ for maintaining a clean, safe warehouse

Administrative offices

Quality filtration to ensure employee well-being and productivity

 

Gain peace of mind for all your sensitive processes

Camfil is a leader in air filtration solutions for the life science industry and works in close cooperation with several of the largest global pharma manufacturers. We offer filters, housings and air cleaners designed to comply with strict demands on safety, traceability and control.

Our complete range of ProSafe™ filters for OSD and pharmaceutical operations offers these benefits:

  • Specially developed for process safety in pharmaceutical environments
  • Inert to microbial growth and contamination in accordance with ISO 846
  • Most energy-efficient filters – their high quality does not compromise operational efficiency
  • Tested resistance to chemicals used for cleaning and decontamination in cleanrooms
  • Free of harmful chemical components such as formaldehyde, phthalates and bisphenol-A
  • Sturdy and resistant to moisture and corrosion for a hygienic HVAC system in accordance with VDI 6022

Camfil’s CleanSeal™ filter housing is also specially designed for life sciences. It is a robust, fully welded, leak-proof solution that is easy to install, handle and maintain.

Benefits of pharmaceutical air filtration solutions from Camfil

Control your sensitive production environment with dedicated pharma air filtration and dust collection solutions. You will gain these benefits:

  • Protect your products from contamination and cross contamination, improving product quality
  • Minimise product rejects and liability
  • Prevent employees from coming into contact with potent compounds, and ensure a high level of comfort
  • Protect the environment by preventing the discharge of chemicals
  • Comply with strict environmental and workplace regulations
  • Minimise operational costs with efficient filter performance

Latest articles

hazard analysis & dust testing help you to fully understand the application & the processed ingredients

Created 08 December 2022

To mitigate exposure and explosion risks in pharmaceutical workspaces, you have to fully understand the application and the processed ingredients. Dust testing and a hazard analysis will provide more specific information about particle size and explosive properties of your dust and thereby to determine the right extraction solution for your needs.

Life science and healthcare

Exposure and explosion risks in the pharmaceutical workplace

Created 08 December 2022

In many instances, pharmaceutical and chemical manufacturing involves the handling and processing of powder or granular ingredients, many of which have exposure or explosion risks attached when in dust form. A comprehensive risk assessment of each and every application is essential before evaluating the appropriate dust control solution.

Life science and healthcare

Containment solutions ensure that dust doesn’t escape during normal operation and routine maintenance

Created 08 December 2022

Active Pharmaceutical Ingredients (API´s) create a number of challenges for pharma manufacturers and their production processes. The API’s create very fine dusts and often high solvent concentrations during the product handling and manufacturing processes. This fine dusts pose the greatest risk to the worker’s health, with harmful particles being retained in the lungs. That´s why effective filtration is required combined with containment solutions to ensure the dust doesn’t escape during normal operation as well as during routine maintenance like filter changes or waste dust disposal.

Life science and healthcare

10 tips on selecting dust collectors for tablet press applications

Created 08 December 2022

Though tablet compression does not generate large volumes of fugitive dust, safe and efficient collection of whatever dust is created by this process is critical. The dust collector linked to the press can contribute to reliable, consistent performance – or detract from it, if components are not properly designed.

Life science and healthcare

Dust collectors are necessary safety systems which have to be maintained properly

Created 07 December 2022

Dust collectors are necessary safety systems in many manufacturing and processing plants, thus as in the food processing industry. But if they are not designed, installed and maintained properly, these systems themselves can cause serious problems. In this eBook we highlight 10 ways how to make sure your dust collection system is up to the tasks of keeping workers safe, maximising production uptime and meeting regulatory compliance.

Food and beverage Manufacturing and Machinery Life science and healthcare

Signs of an underperforming dust collection system

Created 07 December 2022

A properly designed and installed dust collection system will effectively catch, convey and separate hazardous and nuisance dusts. Our new ePoster pinpoints key areas to watch and signs to look for that will help you avoid problems with your dust collection system and to keep up process availability in your production facility.

Food and beverage Manufacturing and Machinery Life science and healthcare

Selecting filter media to optimise performance of your dust extraction system

Created 07 December 2022

For the best possible protection of your processes, products and your employees, you need an effective dust extraction system including the proper filtration media. This eBook outlines five factors you should take into consideration about your dust and process when determining the right filter media.

Food and beverage Manufacturing and Machinery Life science and healthcare

Replacement Cartridge filters and plates for dust extraction systems

Created 07 December 2022

Did you know Camfil have a full range of retrofit filters that can be utilised in all the most common brands on the market. Camfil filters are not just designed to work but to optimise your dust extraction systems performance

Food and beverage Manufacturing and Machinery Life science and healthcare

Mitigate combustion risks & protect from dust explosions

Created 07 December 2022

Almost all industrial manufacturing, processing or packaging applications generate dust as a side effect. Many of these dusts are both combustible as well as explosive, and removing them from the work place can significantly reduce the risk of serious accidents. It is estimated that there are approximately 2,000 dust explosions in Europe annually. Most of these are minor but some are very destructive. So by extracting the dust, the risk in the production is reduced, but unless the extraction system is safe the risk is just moved.

Food and beverage Manufacturing and Machinery Life science and healthcare

Make sure your dust collection equipment is safe & compliant

Created 07 December 2022

Dust collection systems are all safety devices and thus state-of-the art modern methods of validation and certification are required. Furthermore it is vital to ensure that the system is still in compliance after perhaps changed process conditions, to provide maximum safety for personnel and the facility. It is also recommended to carry out quality audits, process reliability surveys and annual safety inspections.

Food and beverage Manufacturing and Machinery Life science and healthcare

Next generation HEPA exhaust housing

Created 25 October 2022

CleanSeal Exhaust Integrity is the next generation of exhaust HEPA housings for sensitive processes. This premium range is designed to ensure a safe operation with critical or hazardous substances. Compliant for ISO14644 testing and allows you to easily inject aerosol together with in situ filter validation scan.

Life science and healthcare

G-CON cleanroom application with Gold Series Dust Collector

Created 26 April 2021

G-CON Manufacturing, a mobile cleanroom provider, and Camfil recently partnered to provide their leading-edge technologies together to meet the needs of a well-known pharmaceutical customer.

Case Studies Life science and healthcare

What is Dust and how to eliminate it

Created 17 February 2021

What is Dust and how to eliminate it

Manufacturing and Machinery Air quality

HEPA FILTRATION-The Changing trends

Created 17 February 2021

HEPA filtration is required in a range of different Industries from Pharmaceuticals, Hospitals, Microelectronics and even the Food and Beverage Industry. Learn about the changing trends in HEPA filtration requirements, How HEPA filtration has advanced over the last number of years and how to identify and reduce the associated costs to your clean air requirements

Life science and healthcare Air quality

HEPA filters and industry standards

Created 17 February 2021

Filtration is a physical, biological or chemical operation that separates solid matter – and sometimes fluids – from a mixture with a filter medium that has a complex structure through which only certain elements of the air (or fluid) can pass.

Standard and regulations Life science and healthcare Air quality

Molecular filtration in Life Science

Created 16 February 2021

Molecular filtration in Life Science

Life science and healthcare Air quality

air cleaners in the life science industry

Created 28 January 2021

Clean air plays an imperative role in the life science, healthcare and pharmaceutical process chain. Many studies have inferred that in moderate levels of air pollution the damage to human health is irreversible. In the life science industry where biological life or living organisms are at play, it is vital to maintain utmost hygiene along with superior indoor air quality. Camfil’s high-efficiency air filtration solutions are used by many global life science industry specialists in cleanrooms, production areas, and laboratories, including many global biosafety labs around the world.

Air cleaners and air purifiers Life science and healthcare Air quality

Camtain® Contains Explosive Pharma Dust

Created 28 November 2018

Case Study: Camtain Contains Explosive Pharma Dust. A multinational pharmaceutical company needed a dust extraction system for their new tableting suite in Spain. The suite comprised of six rooms, each with its own tablet machine that created explosive dusts.

Case Studies Life science and healthcare

Pfizer Improved Air Quality While Cutting Energy Costs

Created 28 November 2018

Pfizer Prioritises Energy Reduction Project. Camfil secured a supply and installation contract at the Pfizer Global Research and Development Campus in South-East Kent, UK that improved air quality and saves over £2 million.

Case Studies

Cannabis Cultivation

Created 28 November 2018

Case Study: Cannabis Cultivation. This key player in the industry operates one of the largest facilities in Canada, with over 150,000 square feet of space licensed for medical marijuana production. The process of growing cannabis produces a strong smell.

Air cleaners and air purifiers Case Studies

Fermentation Odours

Created 28 November 2018

Case Study: Odour Solution For Pharmaceutical Company. There was a distinct odour in the manufacturer's lab and cold storage area, and employee complaints of nuisance odour eventually circulated to management where the concern was escalated.

Case Studies

Gold Series X-Flo

Created 28 November 2018

GSX collectors are ideal for use in pharma, mining, food and chemical processing industries. They also provide a safer work environment in metalworking applications like welding and cutting.

Manufacturing and Machinery

Clean Air Requirements? Contact us today!
Find a contact